How long does the Toniebox 2 remember your auto-saved status when you remove the disc, take a break or play something else?

If you remove your Tonieplay disc for a break or to play another Tonie product, the progress will stop. This means that the game is not "paused" anymore, but you will load it up from scratch again. 

However, each game acts a little differently. For example the quiz games will not continue a running round of let's say 5 questions. An interactive story will be resumable at the last position. A Discover Game will start a new "round".